![]() ![]() Read our recent Q&A with Iram, who is a Wu Tsai Neurosciences Institute Interdisciplinary Postdoctoral Scholar. “We’ve also started to pinpoint which components of the CSF are responsible for the improvement.” Chen Distinguished Professor of Neurology and Neurological Sciences at Stanford and director of the Knight Initiative. “This study shows that there’s something in young CSF that can make the brain function better,” said Tony Wyss-Coray, the senior author of the new paper who is D. The findings open the door for potential new therapeutic targets for aging-related brain diseases like Alzheimer’s and other forms of dementia. Young CSF, they found, could improve memory and cognition in older mice, through effects on the development and function of oligodendrocytes, brain cells that wrap neurons in a fatty, insulating sheath, called myelin, which helps them send long-range signals. Now, with a new study published in Nature, researchers at the Wu Tsai Neurosciences Institute are helping to show that the cerebrospinal fluid that bathes our brains holds clues to healthy brain aging, a major focus of the new Phil and Penny Knight Initiative for Brain Resilience anchored at Wu Tsai Neuro. ![]() Unfortunately, though, modern doctors have little recourse when aging takes its toll on the brain. In the past century, modern medicine has helped drive up average life expectancy in the United States and other developed countries by equipping doctors with the tools and know-how to manage our blood pressure, vaccinate us against dangerous viruses, swap out malfunctioning body parts with prosthetics or transplants, and much more. ![]()
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